ISSN 1662-4009 (online)

ey0019.8-3 | New Mechanisms | ESPEYB19

8.3. DNA methylation signatures in human neonatal blood following maternal antenatal corticosteroid treatment

B Kim , S Sasaki , K Murphy , SG Matthews

Transl Psychiatry. 2022; 12(1): 132. PMID: 35354798https://pubmed.ncbi.nlm.nih.gov/35354798/Brief Summary: This case control study identified widespread effects of fetal exposure to antenatal maternal glucocorticoid treatment on newborn bloodspot DNA methylation profiles.Antenatal treatment with glucocorticoids (AGC), such as betamethasone or dexamethasone, is widely u...

ey0015.1-3 | New mechanisms | ESPEYB15

1.3 Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

Y Zhang , MS Kim , B Jia , J Yan , JP Zuniga-Hertz , C Han , D Cai

To read the full abstract: Nature 2017;548:52-57The central nervous system contributes to ageing. The hypothalamus seems to be particularly important in this process. Recent studies have demonstrated a link between ageing and a decrease of neurogenesis in the hippocampus and the subventricular zone of the lateral ventricle in the brain. Neural stem/progenitor cells (NSC) reside in those regions in ...